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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

4.7
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4,331 ratings

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews

OS

Sep 19, 2019

This course would be most useful to the participant if pursued within a short time-frame, of maximum of 6 weeks. Both lecturers were clear and good communicators. I would take more of their classes.

NP

Oct 4, 2016

The powerpoints and audio lectures are very clear and concise, much appreciated. I would also appreciate more exercises or reading materials, to help solidify our understanding of the topics.

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551 - 575 of 727 Reviews for Design and Interpretation of Clinical Trials

By Tomasz C

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Nov 23, 2019

Very helpful

By Jordon J

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Mar 1, 2018

Really great

By Uriel A P F

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Jan 17, 2018

great course

By Shaker A

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Jun 29, 2017

great course

By Andreas K

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Jun 3, 2017

great course

By Andrea S

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Jan 16, 2017

Great course

By Saddam H

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Jun 17, 2024

Outstanding

By Ehsan M

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Sep 3, 2020

best review

By SUVAM D G

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Jun 11, 2020

Nice course

By Halimah S B

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Apr 27, 2020

THANK YOU .

By Martha S

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Jan 7, 2018

Excellent!!

By Just d i

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Oct 10, 2016

Very useful

By Bruna d S D

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Nov 3, 2022

Excelente!

By Ronei C

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Jul 1, 2022

MUITO BOM!

By Basset B

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May 4, 2020

good cours

By erica s

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Aug 30, 2019

well done.

By Rashad I

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Jul 30, 2017

excellent!

By Beatriz K

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May 2, 2025

Amazing!!

By Vishwa P

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Mar 13, 2022

very good

By MOTUPALLI S H

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Sep 15, 2021

excellent

By RUBEN T

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Apr 29, 2021

very good

By Felipe T G

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Feb 21, 2021

EXCELENTT

By Mario Á

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Jan 2, 2021

Excellent

By asiya p

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Dec 1, 2020

VERY GOOG

By Debanjan D

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Apr 22, 2020

Best Ever